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, Transmissão Vertical de Doenças Infecciosas However, symptomatic COVID-19 was associated with modest increases in preterm delivery and intrapartum fetal distress. CONCLUSIONS: The overall rate of pregnancy complications in women with SARS-CoV-2 infection was similar to that of noninfected women. Among 143 fetuses from infected mothers, none had anti-SARS-CoV-2 IgM/IgA in cord blood. Compared with noninfected women, those with symptomatic COVID-19 had increased rates of preterm delivery (7.2% vs 16.9%, Pâ=â.003) and intrapartum fetal distress (9.1% vs 19.2%, Pâ=â.004), while asymptomatic women had rates that were similar to those of noninfected cases. In women with and without SARS-CoV-2 infection, the primary outcome occurred in 43 (13.6%) and 268 (14%), respectively (risk difference, -0.4% 95% confidence interval, -4.1% to 4.1).

Among positive women, 217 (68.5%) were asymptomatic, 93 (29.3%) had mild coronavirus disease 2019 (COVID-19), and 7 (2.2%) had pneumonia, of whom 3 required intensive care unit admission. Outcomes were also compared between positive symptomatic and positive asymptomatic SARS-CoV-2 women.

#ROBERTA SCIDA PLUS#

Secondary outcomes were components of the primary outcome plus abnormal fetal growth, malformation, or intrapartum fetal distress. The primary outcome was a composite of pregnancy complications in SARS-CoV-2-positive vs negative women that included miscarriage, preeclampsia, preterm delivery, perinatal death, small-for-gestational-age newborn, or neonatal admission. SARS-CoV-2 antibodies (immunoglobulin G and IgM/IgA) were measured in all participants, and nasopharyngeal real-time polymerase chain reaction (RT-PCR) was performed at delivery. METHODS: This prospective, population-based study included pregnant women who consecutively presented at first/second trimester visits or at delivery at 3 hospitals in Barcelona, Spain. For confirmed cases both the mother and the newborn child should be followed up comprehensively.īACKGROUND: We performed a population-based study to describe the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on pregnancy outcomes. CONCLUSION: Overall, due to lack of appropriate data about the effect of COVID-19 on pregnancy, it is necessary to monitor suspected pregnant women before and after delivery. There has been no report of vertical transmission in pregnancy, and it has been found that clinical symptoms of COVID-19 in pregnant women are not different from those of non-pregnant women. RESULTS: A review of 13 final articles published in this area revealed that COVID-19 can cause fetal distress, miscarriage, respiratory distress and preterm delivery in pregnant women but does not infect newborns. All type of articles published about COVID-19 and vertical transmission in pregnancy were included. METHODS: In this narrative review, were searched for all articles published in various databases including PubMed, Scopus, Embase, Science Direct, and Web of Science using MeSH-compliant keywords including COVID-19, Pregnancy, Vertical transmission, Coronavirus 2019, SARS-CoV-nCoV from December 2019 to Maand reviewed them. The present study aimed to review published literature in this regard. INTRODUCTION: The outbreak of the new Coronavirus in China in December 2019 and subsequently in various countries around the world has raised concerns about the possibility of vertical transmission of the virus from mother to fetus. We should not miss the opportunity to learn from this virus about the physiology of pregnancy.

Interference with the vascular adaptations to pregnancy and the post-partum may have implications for concurrent and future pregnancies as well as for long-term cardiovascular health. The manifestation of cardiovascular complications of infection produces the hypothesis that a significant effect of the virus may be its influence on the maternal vascular system. Virus-receptor interactions may have significant effects on placental function, fetal development, and maternal immunity. The currently known receptor for the virus, ACE2, regulates the renin-angiotensin system and is increased during pregnancy. Although the severity of disease in pregnancy does not appear to be increased, the effects of infection on pregnancy should not escape careful examination. Related complications and death from COVID-19 disease and their underlying pathophysiology are intensely investigated.

SARS-CoV-2 has infected more than 16 million people worldwide.

Roberta scida